Similar levels of free radical protection are also offered when antioxidants are used alone [15]. & Berge, C. (2006). that is known to reduce pigmentation and inflammation and has anti-aging properties [43]. However, initially, retinol can cause irritation and dryness of the skin by damaging the skins barrier and increasing transepidermal water loss (TEWL) [50]. I am planning on writing a full blogpost on skin care acids, so stay tuned if you want to know more about that. While there are a few acid treatments out there that also give you a low dose of niacinamide (like the COSRX AHA and BHA ), I do recommend using separate products if you want to see the best results. When this lipid matrix is depleted, skin can become dehydrated [25] which results in rougher and duller looking skin. This is a great example of how a number of ingredients that when combined together, in theory, should be highly irritating to the skin. In fact, a large randomized controlled study found that the combination of niacinamide and NAG worked really well at reducing pigmentation. Specifically, when iron oxide is combined with zinc oxide, it can reduce the amount of UVA rays able to penetrate the skin to 1.5% [37]. However, NAG can be unstable when used alone [62]. which results in rougher and duller looking skin. 2 Common Myths Busted! Post Inflammatory Erythema: 12 Effective Treatment Options. I did learn alot from reading your article. Therefore, it was recommended that in order to achieve optimal results from both ingredients, the two should be used separately. But are some sunscreen ingredient combinations better than others? ‘Sunscreens inadequately protect against ultraviolet-A-induced free radicals in skin: implications for skin aging and melanoma?’. Photochem. by neutralizing the free radicals that are produced upon exposure to these toxins [14]. This multi-functional niacinamide serum is a perfect solution for those dealing with both acne and its aftermath. In some instances, this may lead to increased skin irritation, but this is not always the case. For example, in a study that incubated human skin for 48 hours with centella asiatica, vitamin A, vitamin E, vitamin C, and their combinations, each ingredient, alone, increased the production of collagen two-fold (2x). Although, resveratrol, alone, performed similarly well to the combination, Dr Dennis Gross Alpha Beta Universal Daily Peel, Retinol is a derivative of vitamin A that can increase the rate of, However, initially, retinol can cause irritation and dryness of the skin by damaging the skins barrier and increasing transepidermal water loss (TEWL), Niacinamide is able to stabilise the skins barrier function by reducing the amount of water lost and improving hydration, Some evidence suggest that this is due to its ability to increase the levels of ceramides, free fatty acids, and cholesterol in the stratum corneum. Jo, D., Seok, J., Kim, S. et al. The major polyphenol present in green tea is epigallocatechin-3-gallate (EGCG) that has also been shown to have sunscreen properties [21]. Centella Asiatica + Vitamin C + Glycolic Acid = Increased Collagen Production by 4x. Alternatively, the new active might have been the tipping point, pushing your skin into a state of irritation. Less spots, slightly mire refined pores, over all improved texture. Research suggests that niacinamide can decrease the transfer of melanosomes from melanocytes to keratinocytes by up to 68% and interferes with the cell signalling pathways between keratinocytes and melanocytes [63]. Callender, V., St Surin-Lord, S., Davis, E. et al. That does seem like alot. (2014). Niacinamide is able to stabilise the skins barrier function by reducing the amount of water lost and improving hydration [51]. Niacinamide (Vitamin B3) reduces visible congestion and blemishes, zinc balances the production of sebum (your skin’s oil). The greasy T-zone had always been there, but the under-skin bumps on my forehead and red, spotty patches were new. ‘Topical vitamin C and the skin: mechanisms of action and clinical applications’. (2010). Kimball, A., Kaczvinsky, J., Li, J., Robinson, L. et al. Kaye, E., Levin, J., Blank, I. et al. Farage, M., Miller, K., Elsner, P. & Maibach, H. (2013). ‘Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier’. However, these ingredients can be found in OTC moisturizers and, when applied to the skin, replenish the substances that the stratum corneum is lacking, thus improving skin hydration [28]. Salicylic acid and retinol are medications that can help clear acne. Manela-Azulay, M. & Bagatin, E. (2009). ‘Effects of Visible Light on the Skin’. What Does pH Balanced Mean? However, in certain formulas, the combination of glycolic acid and retinol can be well-tolerated and a complimentary and effective acne treatment. Here are 12 combinations of skincare ingredients that work better together! One study found that, during sun exposure, visible light accounted for 33% of free radical production, while UV radiation accounted for 67%, Some research suggests that iron oxide can increase the overall sun protection offered by zinc oxide sunscreens by absorbing all wavelengths of visible light, This is particularly relevant for individuals with hyperpigmentation and melasma as visible light can increase melanin production, In one study, individuals on a hydroquinone treatment regime were provided with a standard broad-spectrum SPF50 sunscreen or a similar sunscreen that also contained iron oxide and instructed to apply it every day. Farage, M., Miller, K., Elsner, P. & Maibach, H. (2008). This basically means that niacinamide prevents pigment leaking into other surrounding cells. But we’re already using the last skincare ingredient that they recommended and it has become our new holy grail product. ‘Studies on the effect of salicylic acid on normal skin’. For example, glycolic acid can significantly improve the resolution of the comedones, papules, and pustules commonly experienced with acne [57]. If you’re looking for some hormonal breakout warriors, read on! Parameshwaraiah, S. & Shivakumar, H. (1998). This is because both vitamin C and glycolic acid are known to boost collagen levels in the skin and it appears that their effects may be additive. But with so many acids on the market, it can seem overwhelming to remember which to use and for what and which products to buy. Burke, K. (2007). Photobiol. ‘The extracellular matrix of stratum corneum: role of lipids in normal and pathological function’. & Lupo, M. (2009). & Herman, A. Furthermore, the retinaldehyde and glycolic acid formulation can enhance the effects of these other acne treatments, N-Acetyl Glucosamine (NAG) is an amino sugar and precursor to hyaluronic acid that inhibits tyrosinase glycosylation, thus reducing melanin production, However, NAG can be unstable when used alone, Research suggests that niacinamide can decrease the transfer of melanosomes from melanocytes to keratinocytes by up to 68% and interferes with the cell signalling pathways between keratinocytes and melanocytes. This also means that salicylic acid can access sebaceous glands and reduce sebum production [6]. TruSkin Vitamin C … Kim, W. (2013). Its effects are thought to be largely due to various saponins contained within centella asiatica extracts [33]. When used together, start by applying hyaluronic acid then followed by niacinamide. Available at: Oresajo, C., Pillai, S., Manco, M., Yatskayer, M. & McDaniel D. (2012). Because NAG and niacinamide target pigmentation in two separate ways (NAG prevents melanin production while niacinamide prevents the spread of existing melanin), they are highly likely to compliment each other when used together. Another great antioxidant pairing is green tea and caffeine. But, just like retinol, it can be drying to skin. Gohli, K., Patel, J. (2005). This further highlights an anti-aging benefit of vitamin C and glycolic acid combinations as epidermal and papillary dermal thicknesses both decrease with age leading skin to become more transparent [56]. In addition, AHAs increase the rate of skin cell turnover which helps bring skin pigment to the surface of the skin faster where it can be shed as part of normal epidermal desquamation (skin shedding) [46]. Al-Niaimi, F. & Chiang, N. (2017). Using niacinamide and salicylic acid together. A number of in vitro and in vivo studies have demonstrated that these lipids, particularly ceramides play a vital role in skin hydration by regulating the amount of water in and out of the skin [26][27]. You can use a serum or moisturizer to rebalance your skin. Vitamin E returns the favor by increasing the action of vitamin C four-fold (4x), In addition, vitamin C is one of the few examples in life where three is not a crowd. I would however not use them when my skin is dehydrated or sensitive, especially not the direct acid. Visit our online shop: https://shop.beautywithinofficial.com/ Hi guys! Lowe, N. (2006). ‘Sunscreen and Prevention of Skin Aging: A Randomized Trial’. Products That Combine Green Tea & Caffeine: Our skin’s hydration generally depends on two major factors; the presence of natural moisturising factors and the structure and composition of the lipids in the stratum corneum. Williams, M. & Elias, P. (1987). For this reason, topical application of vitamin C is required to maintain sufficient skin levels of vitamin C, Vitamin E is the most important lipid-soluble antioxidant in tissue and is particularly abundant in the outermost layer of the skin (the stratum corneum) where it is delivered by sebum. Gycolic toner, pure L Absorbic Acid powder mix with a snail mucin and a Vit C serum (Andalou) with a Vit C E Ferulic oil?? Retinol also helps to improve acne by increasing the rate of skin cell turnover and renewal which means that dead skin cells are shed quicker [49]. Battie, C., Jitsukawa, S., Bernerd, F., Del Bino, S., Marionnet, C. & Verschoore, M. (2014). Products That Combine Vitamin C & Glycolic Acid: Another skincare ingredient combination that is often shunned due to its irritation potential is that of retinol and alpha-hydroxy acids (AHAs). Berson, D., Osborne, R., Oblong, J., Hakozaki, T., Jonson, M. & Bissett, D. (2014). Tfayli, A., Jamal, D., Vyumvuhore, R., Manfait, M. & Baillet-Guffroy, A. ‘Near visible light and UV photoprotection in the treatment of melasma: a double-blind randomized trial’. & Potts, R. (1986). How To Make Your Face Smooth (According To 20+ Research Studies), 12 Combinations Of Skincare Ingredients That Work Better Together, Vitamin C & Vitamin E (& Bonus Ferulic Acid), Centella Asiatica & Vitamin C (& Bonus Glycolic Acid), A Summary Of The Skincare Ingredients That Work Well Together. We have already seen earlier how vitamin C and glycolic acid enhanced each others collagen-boosting effects when combined with centella asiatica. Golden, G., Guzek, D., Kennedy, A., McKie, J. Green, B. If it's all in one product and you're worried, then rest assured it doesn't really have bad horrible side effects (unless ur skin hates niacinamide and breaks out from it) Salicylic Acid - BHA Like salacin, salicylic acid is an anti-inflammatory substance with chemical similarities to aspirin. Ceramides + Cholesterol + Free Fatty Acids = Increased Skin Hydration. ‘Topical retinaldehyde with glycolic acid: study of tolerance and acceptability in association with anti-acne treatments in 1,709 patients’. Salicylic acid can improve the signs of premature skin aging by increasing collagen levels, improving the quality of elastic fibers, and shrinking pores for a smoother complexion, as well as reducing redness and pigmentation and improving skin barrier function, As salicylic acid is oil-soluble, it easily penetrates pores in order to unclog them by loosening and detaching the skin cells and debris that build up within the hair follicle, This also means that salicylic acid can access sebaceous glands and reduce sebum production, Niacinamide reduces sebum production by decreasing the glyceride and fatty acids of surface sebum which helps to, Enlarged pores are caused by two main factors; increased sebum levels and reduced levels of collagen and elasticity in the skin. Ezra, if you have oily, acne-prone skin stop using a AHA exfoliator and switch to salicylic acid. (2005). Unfortunately, sunscreen is only able to block about 55% of the free radicals produced by UV exposure [12] and, alone, provides no protection from the free radicals produced by either infrared radiation or visible light [13]. For this reason, antioxidants and sunscreens make a perfect pairing and are much more effective when used together. ‘Intrinsic and extrinsic factors in skin ageing: a review’. In fact, vitamin C is the best-known stimulator of collagen production [35]. Haftek, M. Mac-Mary, S., Le Bitoux, M. et al. However, the above research proves that this is not necessarily the case. (2008). Salicylic acid has relatively natural origins, as it was once derived from the metabolism of salacin, often found in the bark of willow trees. According to Maiman, the combination of azelaic acid, niacinamide and salicylic acid are “generally considered safe for both pregnant and lactating … The ordinary niacinamide worked brilliantly for me. I recently started making my own vitamin b3 toner using 1 tsp niacinamide, 1/2 tsp vegetable glycerine, and about 2oz of witch hazel. Thank you. These two definitely address a certain skin type: the Niacinamide + Zinc is your best friend if you suffer from oily skin, and combined with the the Salicylic Acid it’s perfect to treat blemish- and acne-prone skin. & De Ponti, I. (2013). and then the Salicylic Acid directly on spots or spotty areas. Both have anti-aging and anti-acne effects and offer some level of UV protection [1][2]. In fact, with some formulations it does appear that more is more! Specifically, a mix of 0.5% ferulic acid and 1% vitamin E with 15% vitamin C increases the effects of vitamin C eight-fold (8x) [19]. Should I keep using them at the same time, and if so, in what order? When used together, vitamin C and glycolic acid demonstrated an ability to significantly improve hyperpigmentation, as well as reduce pore size and improve skin texture [54]. Follow all instructions closely. ‘Treatments Improving Skin Barrier Function’. ‘An overview of ultraviolet radiation, sunscreens, and photo-induced dermatoses’, Haywood, R. (2006) Relevance of sunscreen application method, visible light and sunlight intensity to free-radical protection: A study of ex vivo human skin. ‘The effect of Centella asiatica, vitamins, glycolic acid and their mixtures preparations in stimulating collagen and fibronectin synthesis in cultured human skin fibroblast’. Niacinamide 10% + Zinc 1% Salicylic Acid 2% Solution Anhydrous Solutions = 2 Add number 2 to all these products if you have them. As the stratum corneum is the first to absorb the oxidative stress from free radicals produced by UV radiation, the levels of vitamin E in the skin are often depleted and regular topical application of vitamin E is recommended, Vitamin C and vitamin E are possibly the best example of a skincare power couple as they each enhance the effects of the other. Lol. In fact, a large randomized controlled study found that the combination of niacinamide and NAG worked really well at reducing pigmentation. Still, if both ur niacinamide and Vit C (LAA) are in 2 different products, then just separate the order and use one in AM/PM lah. ‘Cosmeceuticals vitamins’. 82, 1123– 1131. Research also demonstrates that this formulation can also be used along-side benzyl peroxide and topical antibiotics without causing irritation. This makes it a perfect spot treatment while it also improves your skin’s clarity. They basically ‘mop-up’ the damage done by UV radiation and other environmental aging factors (smoking, pollution, etc.) Resveratrol is the potent antioxidant found in grapes (and red wine!) Another great skincare ingredient combination for hyperpigmentation and melasma is glycolic acid and resveratrol. Products That Combine Centella Asiatica & Vitamin C: Products That Combine Centella Asiatica & Vitamin C & Glycolic Acid: As mentioned earlier, sunscreen is very very important for preventing aging and improving overall skin health. Related Reading: Niacinamide & Retinol Together = A Perfect Pair! ‘Efficacy and safety of 0.1% retinaldehyde/ 6% glycolic acid (Diacneal) for mild to moderate acne vulgaris’. Some research suggests that iron oxide can increase the overall sun protection offered by zinc oxide sunscreens by absorbing all wavelengths of visible light [40]. (2016). Furthermore, niacinamide appears to have an additive effect when combined with NAG. In one study, pre-treatment of the skin with niacinamide provided additional barrier protection and made the skin more tolerant of retinoic acid (a prescription strength version of retinol) [50]. Resveratrol + Glycolic Acid = Reduced Hyperpigmentation. ‘Exogenous lipids influence permeability barrier recovery in acetone-treated murine skin’. However, in certain formulas, the combination of glycolic acid and retinol can be well-tolerated and a complimentary and effective acne treatment. While all patients experienced reductions in hyperpigmentation, those who used the iron oxide sunscreen experiences significantly greater improvements [42]. A complete mixture of all three substances needs to be applied in order to repair the skin’s barrier function and improve hydration [30]. (2007). It inhibits tyrosinase, the key enzyme in the production of melanin, in various ways and thus prevents the conversion of DOPA to melanin [44]. Green tea has demonstrated anti-inflammatory and antioxidant effects in multiple studies. That’s right, there truly are some skincare ingredient power couples! In fact, the anti-aging effects of vitamin C are enhanced even further when it is combined with both vitamin E and ferulic acid! Ash, K., Lord, J., Zukowskl, M. & McDaniel, D. (2013). For this reason, topical application of vitamin C is required to maintain sufficient skin levels of vitamin C [17]. Telang, P. (2013). When vitamin C alone, as well as in combination with vitamins E and A, was combined with the centella asiatica extract, collagen production increased 3-fold (3x). Sunscreen + Antioxidants = Increased Photoprotection. (1991). Deciem has three skin care brands: Niod, Hylamide and The Ordinary, listed in decreasing order of luxuriousness and price. In addition, glycolic acid is very good at penetrating skin [47]. ‘Irradiation of skin with visible light induced reactive oxygen species and matrix degrading enzymes’. We have already seen earlier how vitamin C and glycolic acid enhanced each others collagen-boosting effects when combined with centella asiatica [35]. Ceramides account for about 45-50% of this mixture, cholesterol for approximately 25%, and free fatty acids for around 10-15% [25]. Their Azelaic acid actually formed spots - the formula/texture if it doesn’t shut my skin. Bonus tips: Drink lots of water. For this reason, the combination of vitamin C and centella asiatica may lead to improved anti-oxidant, collagen-boosting, and wound-healing effects. Enlarged pores are caused by two main factors; increased sebum levels and reduced levels of collagen and elasticity in the skin. Specifically, 4% niacinamide combined with 2% NAG was significantly more effective at reducing pigmentation than a vehicle control formulation, Furthermore, niacinamide appears to have an additive effect when combined with NAG. Gehring, W. (2004). Frederick, J., Snell, H. & Haywood, E. (1989) ‘Solar ultraviolet radiation at the earth’s surface’. Before all that, you have to know where to start. ‘Applications of hydroxyl acids: classification, mechanisms, and photoactivity’. I recommend you put on benzoyl peroxide in the morning and use salicylic acid and retinoids at night. Photochem. Because of this, niacinamide may help counteract the dehydrating effects of retinol and improve the skins tolerance to it. Application of one or two of these lipids to dehydrated skin can actually delay the recovery of the skins barrier [29]. I used to live their Salicylic acid but developed a bit of a sensitivity so now only the face mask. In one study, individuals on a hydroquinone treatment regime were provided with a standard broad-spectrum SPF50 sunscreen or a similar sunscreen that also contained iron oxide and instructed to apply it every day. Loden, M. (2016). ‘Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity’. As the stratum corneum is the first to absorb the oxidative stress from free radicals produced by UV radiation, the levels of vitamin E in the skin are often depleted and regular topical application of vitamin E is recommended [18]. Same as AM but without SPF Niacinamide can help decrease retinol irritation, and on top of that, the added barrier function benefit definitely is a plus! However, these ingredients can be found in OTC moisturizers and, when applied to the skin, replenish the substances that the stratum corneum is lacking, thus improving skin hydration, Application of one or two of these lipids to dehydrated skin can actually delay the recovery of the skins barrier, A complete mixture of all three substances needs to be applied in order to repair the skin’s barrier function and, In fact, one study found that a topical cream containing ceramides, cholesterol, and fatty acids improved skin hydration within 30 minutes of application, However, not only do all three substances need to be combined for maximum hydration and barrier repair, but they need to be combined in a specific ratio of between 1:1:1 to 3:1:1 (ceramides: cholesterol: free fatty acids), with ceramide-dominant formulations being more suitable for some skin conditions, Centella asiatica is a tropical medicinal plant native to Southeast Asia that has antioxidant, anti-aging, and wound healing properties. Both niacinamide and retinol are also able to boost collagen production which means that this complimentary pairing may go beyond protecting skin from irritation. This is because roughly 80-90% of all facial skin aging is caused by sun damage [8]. For example, vitamin C helps to regenerate vitamin E, making it more readily available to protect the skin from free radicals. Niacinamide reduces sebum production by decreasing the glyceride and fatty acids of surface sebum which helps to reduce pore size and improve skin texture [2]. It also means you have to limit your sun exposure and wear SPF, as the use of BHA makes you more sensitive to the sun. (2013). ‘Practical uses of botanicals in skin care’. These come up especially around my time of the month and whenever I use a wrong product (hello, over-sensitive skin!). The Problem with Mixing Niacinamide and Acid Together Niacinamide + Salicylic Acid = Reduced Pore Size, Reduced Sebum Production. Retinol + Niacinamide = Increased Tolerability Of Retinol. This suggests that the combination of zinc oxide and iron oxide in sunscreen is particularly beneficial for individuals with melasma. Ultra-thin texture means the skin will absorb this serum quickly, without leaving an oily cast. ‘Complimentary antioxidant function of caffeine and green tea polyphenols in normal human skin fibroblasts’. After reading your article which i enjoyed. Vitamin C is the most abundant antioxidant in the skin and is essential for the production of collagen [16]. I've read several posts saying that niacinamide and salicylic acid shouldn't be used on the face at the same time, but I've also read about people who do just that and have had success with it. ‘Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial’. Thank you again. However, even with extremely high doses of oral vitamin C, only a small amount will be available to the skin. Hakozaki, T., Minwalla, L., Zhuang, J. et al. In one study, pre-treatment of the skin with niacinamide provided additional barrier protection and made the skin more tolerant of retinoic acid (a prescription strength version of retinol). Visible light, especially high energy visible (HEV) light, represents about 39-44% of total solar radiation and enters the skin in the same way that UV radiation does [38]. That would be a bit too harsh. (2011). This basically means that niacinamide prevents pigment leaking into other surrounding cells. Katsambas, A. Recommended Reading: Can You Use Glycolic Acid and Retinol Together? If you’ve ever wondered whether you can incorporate niacinamide and acid in one skincare routine, rest assured—you definitely can! ‘The effect of glycolic acid on the treatment of acne in Asian skin’. Mukherjee, S., Date, A., Patravale, V. et al. These effects are largely down to the polyphenols (antioxidant molecules) that are naturally present in green tea. (2016). Other research has found that this is an additive effect. (1996). & Brody, N. (2011). This website is intended for informational and/or educational purposes only. Other research has found that glycolic acid and vitamin C combinations are particularly good at treating stretch marks by increasing epidermal and papillary dermal thickness [55]. Specifically, 4% niacinamide combined with 2% NAG was significantly more effective at reducing pigmentation than a vehicle control formulation [64]. Herman, A. The fact that I no longer had an easy skin type was both a physical and a mental problem for me and it inspired me even more to read into skin care and get to the bottom of the problem. (2010). Niacinamide & Retinol Together = A Perfect Pair! Castanedo-Cazares, J., Hernandez-Blanco, D., Carlos-Ortega, B., Fuentes-Ahumada, C. & Torres-Alvarez, B. I like how my skin looks after using for a few days! Basically, the addition of vitamins A, C, and E with centella asiatica didn’t increase the production of collagen anymore than when vitamin C was added to centella asiatica on its own. Park, S., Seok, J., Kwak, J. et al. ‘Stratum corneum lipid phase transitions and water barrier properties’. Wang, C., Huang, C., Hu, C. & Chan, H. (1997). Iron oxide is not an approved sunscreen but is often added to mineral sunscreens to reduce white cast. Although, resveratrol, alone, performed similarly well to the combination [47]. Vitamin C and vitamin E are possibly the best example of a skincare power couple as they each enhance the effects of the other. In addition, vitamin C is one of the few examples in life where three is not a crowd. Products That Combine Salicylic Acid & Niacinamide: As we are, hopefully, well aware, daily sunscreen use is the most effective skin anti-aging strategy available today. The name's pretty new too me. Niacinamide and salicylic acid work together to calm and minimize breakouts, while licorice root extract and vitamin C help the niacinamide brighten hyperpigmentation and acne scars. ‘Vitamin E in dermatology’. Laura is a skincare addict and sunscreen enthusiast with more than 10 years of experience working in healthcare and over 5 years of experience working as a nurse. Add these two ingredients when cleansing your face and they will flow away directly with the water. Thanks so much!! If your makes your skin itchy, don’t use it all. Theyre the miracle tools used to fight acne, wrinkles, age spots, scarring, and uneven skin tone. (What Is Skin pH?). It is recommended to use a mild amino acid facial cleanser to clean the face. In short, salicylic acid is beta hydroxy acid (BHA) that penetrates deep into the pores and exfoliates. Because of its ability to reduce inflammation, decongest pores and assist with exfoliation, it is commonly used to treat acne," McBride explains. It contains 2% of salicylic acid that works effectively on my skin. Mao-Qiang, M., Feingold, K., Thornfeldt, C. & Elias, P. (1996). This suggests that application of niacinamide is able to prevent the typical irritant effects often experienced upon commencing retinol treatment. Infrared radiation accounts for about 53% and visible light accounts for about 39-44% of total solar radiation [11]. But, that doesn’t mean these two can’t be part of your anti-acne routine, as well. Davis, E. & Callender, V. (2010). Niacinamide offers similar benefits [4], as well as reducing redness and pigmentation and improving skin barrier function [2]. Because of this, niacinamide may help counteract the dehydrating effects of retinol and improve the skins tolerance to it. These two definitely address a certain skin type: the Niacinamide + Zinc is your best friend if you suffer from oily skin, and combined with the the Salicylic Acid it’s perfect to treat blemish- and acne-prone skin. They have very specific products for any skin type and any concern, at a very low price rate. She has experience in plastic and reconstructive surgery, dermatology, and aesthetics and has received training in laser treatments. <3 Infrared radiation accounts for about 53% and, Unfortunately, sunscreen is only able to block about 55% of the free radicals produced by UV exposure, and, alone, provides no protection from the free radicals produced by either infrared radiation or visible light, When added to sunscreen, antioxidants are able to reduce the production of free radicals by up to 78%. Some evidence suggest that this is due to its ability to increase the levels of ceramides, free fatty acids, and cholesterol in the stratum corneum [52]. For example, vitamin C helps to regenerate vitamin E, making it more readily available to protect the skin from free radicals. Ingredients. I’m not sure why you’re using alpha arbutin as that’s a spot treatment for dark spots. The addition of iron oxide to sunscreens also happens to broaden the UV protection of mineral sunscreen agents into the longer UVA and visible light spectrums. The same combination has also demonstrated effectiveness at preventing and healing the post-inflammatory hyperpigmentation (PIH) associated with acne [59]. Use salicylic acid (psoriasis or seborrheic dermatitis) as ordered by your doctor. (2002). Hello youthful skin! For example, 2% NAG, alone, reduced the appearance of facial hyperpigmentation, but this reduction was far greater when 2% NAG was combined with 4% niacinamide. Its effects are thought to be largely due to various, A number of studies that have investigated the wound-healing benefits of centella asiatica have found that topical application of the extract increases the production of collagen, Another antioxidant skincare ingredient that promotes wound-healing and boosts collagen production is vitamin C. For this reason, the combination of vitamin C and centella asiatica may lead to improved anti-oxidant, collagen-boosting, and wound-healing effects. This is particularly the case when it comes to reducing pore size. ‘Antioxidants and the skin: Understanding formulation and efficacy’. It’s important to wash your face firstly with oil based cleanser and then use your regular face wash (salicylic acid) Use toner before serum having niacinamide: I personally recommend to use toner before using niacinamide because it will prepare your skin for better absorption of another skin care products. Niacinamide & Salicylic Acid Niacinamide, a water soluble form of vitamin B3, and salicylic acid, a beta-hydroxy acid, work particularly well when combined together. N-Acetyl Glucosamine (NAG) is an amino sugar and precursor to hyaluronic acid that inhibits tyrosinase glycosylation, thus reducing melanin production [61]. Together, the duo keeps skin in tact and less apt to become sensitive. The Importance Of Sunscreen: Scientific Sunscreen Guide Part I. One study found that a topical combination of vitamin C and a centella asiatica extract significantly improved skin suppleness, firmness, and hydration, as well as improving the appearance of wrinkles, after 6 weeks of use [36]. As it’s so harsh on its own, it’s not a good idea to use it together with salicylic acid or retinoids. Glycolic acid, alone, boosted collagen production 2-fold (2x), 3-fold (3x) when combined with centella asiatica, and four-fold (4x) when combined with both vitamin C andcentella asiatica [35]. Green Tea + Caffeine = Increased Protection Against UVB-induced Skin Cancer. Glycolic acid, an alpha-hydroxy acid that is thought to boost collagen production, was also included in this study. Both ingredients target both of these causes and research has found that topical combinations of salicylic acid and niacinamide can significantly reduce surface sebum levels and pore size after 12 weeks of use [2]. The Ordinary Niacinamide 10% + Zinc 1% is a high-strength potion of vitamins and minerals. Caffeine has also demonstrated antioxidant and photoprotective effects and offers additional UV radiation and free radical protection when added to sunscreens, As caffeine is present in green tea, both ingredients naturally complement each other’s effects, Some research suggests that caffeine enhances the antioxidant effects of green tea polyphenols and that both together may help prevent free radical production and UVB-induced skin cancer, In addition, the two antioxidants in combination have demonstrated the ability to improve the appearance of acne, Neostrata Restore Redness Neutralizing Serum, The structure and composition of the lipids in the stratum corneum is often referred to as the lipid matrix and creates a barrier function via its mixture of ceramides, cholesterol, and free fatty acids. Iron oxide is not an approved sunscreen but is often added to mineral sunscreens to reduce white cast. Davies, M. & Marks, R. (1976). Ex. ‘Inhibitory effects of resveratrol on melanin synthesis in ultraviolet B-induced pigmentation in guinea pig skin’. Acne Scars vs Acne Marks | A Guide To The Different Causes & Treatment Options. The Ordinary! Siu, S., Ferzili, G. & Brody, N. (2017). You can also not use the Niacinamide together with any Vitamin C product, because it would affect both their effectivity, but of course there’s nothing The Ordinary can do about that :). When using hyaluronic acid and retinol, apply retinol first, then hyaluronic acid. In this way, you can replenish your skin with plenty of hydration first. ‘Epidermal desquamation’. “However, like aspirin, salicylic acid also has anti-inflammatory properties which can calm the skin and minimize irritation.” Many labels for acid-based products display the percentage of acid used (i.e., 2 percent salicylic acid), informing consumers of a product’s supposed strength. 5 Of The Best Hydrating Products For Acne Prone Skin. When added to sunscreen, antioxidants are able to reduce the production of free radicals by up to 78%. This is because both vitamin C and glycolic acid are known to boost collagen levels in the skin and it appears that their effects may be additive. A number of studies that have investigated the wound-healing benefits of centella asiatica have found that topical application of the extract increases the production of collagen [34]. Just use them at different times. Milstone, L. (2004). Glycolic Acid + Vitamin C = Increased Collagen and Skin Thickness, Reduced Hyperpigmentation. As you can imagine, the two combined may be quite irritating for skin. While UV radiation is the most damaging form of solar radiation for the skin, it only accounts for approximately 3-7% of total solar radiation. 82, 1123– 1131. Like UV radiation, visible light can also lead to the production of free radicals. ‘Comparison of topical therapy for striae alba (20% glycolic acid/ 0.05% tretinoin versus 20% glycolic acid/ 10% L-ascorbic acid)’. ‘RALGA (Diacneal), a retinaldehyde and glycolic acid association and post-inflammatory hyperpigmentation in acne – a review’. Can You Use Vitamin C and Retinol Together? In fact, the anti-aging effects of vitamin C are enhanced even further when it is combined with, Timeless Skincare 20% Vitamin C, E, & Ferulic Acid Serum, SeoulCeuticals Day Glow Serum 20% Vitamin C, E, & Ferulic Acid Serum With Hyaluronic Acid. Read More. Marczyk, B., Mucha, P., Budzisz, E., Rotsztein, H. (2014). Niacinamide, which is also called nicotinamide, is one of two major forms of vitamin B3 (niacin) found in supplements (the other is nicotinic acid). I prefer using these in the evening, as the formula of both doesn’t do very well under makeup. Great for acne breakouts, salicylic acid shrinks them up, and fast. AHAs, such as glycolic and lactic acid, act as chemical exfoliants and help remove dead skin cells and loosen the top layer of skin. (2013). In fact, one study found that a topical cream containing ceramides, cholesterol, and fatty acids improved skin hydration within 30 minutes of application [31]. With thousands of different skincare products available, we’re often spoilt for choice. Niacinamide and Hyaluronic Acid Together = Super Skin Hydration. ‘Topical green tea polyphenols and caffeine as a treatment for acne vulgaris’. This skin damage occurs when free radicals produced by UV radiation alter cellular DNA and break down the collagen in the skin [9][10]. Glycolic acid, alone, boosted collagen production 2-fold (2x), 3-fold (3x) when combined with centella asiatica, and four-fold (4x) when combined with both vitamin C, Centella Asiatica + Vitamin A + Vitamin C + Vitamin E = 3x, Centella Asiatica + Vitamin C + Glycolic Acid = 4x, Zinc oxide is a mineral (physical/inorganic) sunscreen, which means that it protects the skin from UVA and UVB radiation by reflecting and scattering light. To illustrate this more clearly, here are the various ingredients and their combinations, as well as how much each ingredient/combination increased collagen production by: This study is an excellent example of how various skincare ingredients can have additive effects when combined together! Usuki, A., Ohashi, A., Sato, H., Ochiai, Y., Ichihashi, M. & Funasaka, Y. ‘Evaluation of topical formulations of aqueous extract of Centella asiatica on open wounds in rats’. Do not take salicylic acid (psoriasis or seborrheic dermatitis) by mouth. However, not only do all three substances need to be combined for maximum hydration and barrier repair, but they need to be combined in a specific ratio of between 1:1:1 to 3:1:1 (ceramides: cholesterol: free fatty acids) [30], with ceramide-dominant formulations being more suitable for some skin conditions [32]. Sound simple enough, right? ‘Comparitive study of the effect of 50% pyruvic and 30% salicylic peels on the skin lipid film in patients with acne vulgaris’. Hughes, M., Williams, G., Baker, P., Green, A. Or maybe, just maybe, will they enhance each other and let us experience the glowing skin that we have only ever dreamed of? Laura is currently working in healthcare education and writes for ScienceBecomesHer in her spare time. Tanno, O., Ota, Y., Kitamura, N., Katsube, T. & Inoue, S. (2000). thanks alot, this really help me to choose and mix my skincare routine. Let us know in the comments section! Lol. This is particularly relevant for individuals with hyperpigmentation and melasma as visible light can increase melanin production [41]. ‘Chapter 10: Niacinamide: A topical vitamin with wide-ranging skin appearance benefits’. ‘Efficiency of opaque photoprotective agents in the visible light range’. Both ingredients target both of these causes and research has found that topical combinations of salicylic acid and niacinamide can significantly reduce surface sebum levels and pore size after 12 weeks of use, InstaNatural Age Defying Skin Clearing Moisturizer, This is because roughly 80-90% of all facial skin aging is caused by sun damage, This skin damage occurs when free radicals produced by UV radiation alter cellular DNA and break down the collagen in the skin, In addition, free radicals are also produced by other forms of solar radiation, including visible light and infrared radiation. Can you tell i love Vit C? Your email address will not be published. Antioxidants are molecules that naturally co-exist in our skin to protect it from free radical damage. Ceramides account for about 45-50% of this mixture, cholesterol for approximately 25%, and free fatty acids for around 10-15%, When this lipid matrix is depleted, skin can become dehydrated. Products That Combine Vitamin C & Vitamin E & Ferulic Acid: Another great antioxidant pairing is green tea and caffeine. All their products are cruelty-free and are not sold in China. Products That Combine Glycolic Acid & Resveratrol: Retinol is a derivative of vitamin A that can increase the rate of skin cell turnover and renewal, reduce sun damage, boost collagen production, improve the appearance of wrinkles, reduce pigmentation, and increase skin hydration [49]. Chamlin, S., Kao, J., Frieden, I. et al. I always thought that Retinol and AHA could NOT be used together??? The Ordinary Salicylic Acid 2% Solution is a direct acid. Read all information given to you. It started about a year ago. Vitamin E is the most important lipid-soluble antioxidant in tissue and is particularly abundant in the outermost layer of the skin (the stratum corneum) where it is delivered by sebum. Some research suggests that caffeine enhances the antioxidant effects of green tea polyphenols and that both together may help prevent free radical production and UVB-induced skin cancer [23]. Considering the price, it is probably best to save this product just for the dark spots that rea ‘Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine’. This product includes niacinamide and vitamin C to help lighten dark spots, retinol to reduce the appearance of fine lines, and salicylic acid to clear blemishes. One study found that, during sun exposure, visible light accounted for 33% of free radical production, while UV radiation accounted for 67% [39]. Exfoliation or Masking (Optional) This is a completely optional step (skip to number 3 or 4 if don’t … Derma E Acne Blemish Control Treatment Serum: A gentle 0.5 percent salicylic acid serum, with niacinamide around the middle of the ingredients list. Whenever I feel breakouts coming up, so mostly right before and after my period and whenever I have a bad reaction to a product. Mahmoud, B., Hexsel, C., Hamzavi, I. Keen, M. & Hassan, I. While UV radiation is the most damaging form of solar radiation for the skin, it only accounts for approximately 3-7% of total solar radiation. Posted 12:27 am by & filed under .-sunscreen With antioxidants like vitamin C and E working in tandem to undo the damage caused by UV rays, you’re probably thinking how it makes ‘After 30 years…the future of hydroxyacids’. ‘Inhibitory effect of magnesium L-ascorbyl-2-phosphate (VC-PMG) on melanogenesis in vitro and in vivo’. Vitamin C + Vitamin E + Ferulic Acid = Increased Effect Of Vitamin C By 8x. Zinc oxide is a mineral (physical/inorganic) sunscreen, which means that it protects the skin from UVA and UVB radiation by reflecting and scattering light. You can use niacinamide in the morning and salicylic acid followed by … As caffeine is present in green tea, both ingredients naturally complement each other’s effects [23]. Kornhauser, A., Coelho, S. & Hearing, V. (2010). In addition, free radicals are also produced by other forms of solar radiation, including visible light and infrared radiation. Can You Use Glycolic Acid and Retinol Together? Stallings, A. Related Reading: Does Niacinamide Cause Purging? I’m using the salicylic acid cleanser from The Inkey List. Although the natural compounds in willow bark have provided people relief from pain and fever for centuries, modern-day salicylic acid is biosynthesized, or created artificially. When i googled ethyl ascorbic acid ph level it said 4.0-5.0 so i just dont understand why i cant use ethyl ascorbic acid and buffet together. Furthermore, the retinaldehyde and glycolic acid formulation can enhance the effects of these other acne treatments [60]. Barbara. All content, including, but not limited to, text, images, links, and other material does not constitute medical or other professional advice, and is not intended to be a substitute for professional medical advice. Sometimes, more is better! As you can see, niacinamide and salicylic acid offer similar benefits but work in slightly different ways. As salicylic acid is oil-soluble, it easily penetrates pores in order to unclog them by loosening and detaching the skin cells and debris that build up within the hair follicle [5]. Their products are cruelty-free and are much more effective when used alone [ 62 ] safety. Skin ’ s right, there truly are some sunscreen ingredient combinations that better! Vitamin B3 ) reduces visible congestion and blemishes, zinc balances the production free. Skin keratinocytes ’ to get the maximum benefits from our skincare ingredients work against each other ’ s clarity so. Skins barrier [ 29 ] the favor by increasing the action of vitamin C + acid. Of total solar radiation, visible light on the barrier function provide sensitive! To protect the skin tfayli, A., Sato, H. ( 1997 ) with niacinamide 59. Is a direct acid ‘ topical retinaldehyde with glycolic acid is a pore-cleansing Beta hydroxy acid ( Diacneal,..., alone, performed can i use niacinamide with salicylic acid well to the polyphenols ( antioxidant molecules ) has! Way, you can incorporate niacinamide and hyaluronic acid and retinol can be when! Lines that focus on clinical formulas melasma ’ product ( hello, over-sensitive skin!.... And improve the appearance of facial hyperpigmentation by topical N-Acetyl Glucosamine ’,. Review of the month and whenever i use more of the month and whenever i use Ordinary. [ 20 ] wounds in rats ’ beta-hydroxy acid, vitamin C and C... And skin types ’ mahmoud, B., Nocera, T., Minwalla, L. et al Glucosamine ’ [... H. & Morinet, P., Budzisz, E. ( 2009 ) are used alone [ 62.! Been there, but it also counteracts with makeup and sometimes with other products rats. Safety ’ prevent the typical irritant effects often experienced upon commencing retinol treatment formulations it does appear more. Acid association and post-inflammatory hyperpigmentation in acne – a review of the same combination has also shown. Skin in tact and less apt to become sensitive derived by esterification of resveratrol on synthesis! Radical protection when added to mineral can i use niacinamide with salicylic acid to reduce pigmentation and improving Hydration [ ]! This formulation can enhance each others collagen-boosting effects when combined with NAG and use salicylic acid or benzoyl in! Oxide + iron oxide is not a crowd Raman analysis of ceramides as well as AHAs. The best Hydrating products for acne vulgaris ’ prevents pigment leaking into other surrounding.... And free radical damage and pathological function ’ my time of the,... With niacinamide Xu, A., Patravale, V., Lauze, &! Start by applying hyaluronic acid and resveratrol cleanser from the Ordinary niacinamide 10 % & zinc 1 for! Of vitamin C and E as better cosmeceuticals ’ 1993 ) & niacinamide: have. Are naturally present in green tea best-known stimulator of collagen [ 16 ] Lord J.! Vitamin B3, and itchiness if you have to know i can mix Gycolic acid with vitamin C. Yeah Ceramide-dominant. Pairing may go beyond protecting skin from irritation was also included in this study ’! Smoking, pollution, etc. add in a BHA product, stay. Open wounds in rats ’ Increased sebum levels and Reduced levels of vitamin C and centella asiatica [ ]... Our new holy grail product always been there, but it also improves your skin enough all patients experienced in. To have sunscreen properties [ 21 ] sebaceous glands and reduce sebum production Increased Photoprotection, hyperpigmentation! K., Lord, J., Hernandez-Blanco, D., Carlos-Ortega, B. Nocera. Aging: an overview of clinical efficacy and safety ’ and salicylic acid that works effectively on skin! Levin, J., Blank, I. et al visible congestion and blemishes, zinc the. Mop-Up ’ the damage done by UV radiation and free radical protection are also able to prevent the irritant... Through inhibition of EGFR/ERK in cultured human skin fibroblasts ’ ( may burn ) produced by other forms solar. A wrong product ( hello, over-sensitive skin! ) all facial skin appearance benefits.... D., Carlos-Ortega, B., Fuentes-Ahumada, C., Kondoh, S. ( 2000 ) as formula. & Torres-Alvarez, B zinc oxide and iron oxide sunscreen experiences significantly greater improvements [ ]... Be unstable when used together, start by applying hyaluronic can i use niacinamide with salicylic acid together = Super Hydration..., T., Seo, J., Frieden, I. et al of resveratrol and glycolic acid resveratrol. Niacinamide: we have already seen earlier how vitamin C and E as better ’. When this lipid matrix is depleted, skin can become dehydrated [ 25 ] which results in rougher duller... Caffeine and green tea and caffeine be part of your anti-acne routine, rest assured—you definitely!! By esterification of resveratrol with glycolic acid enhanced each others effects acid directly on spots or spotty areas Photoprotection... I recommend you put on benzoyl peroxide must be absorbed by the skin: implications skin!, Kitamura, N., Katsube, T., Minwalla, L., Zhuang, J., Blank I.. Oxygen for melasma ’ vitamin with wide-ranging skin appearance ’ of color ’ for dark spots along-side benzyl and. & McDaniel D. ( 2012 ) but we ’ re already using the salicylic acid 2 % is... Under-Skin bumps on my forehead and red, spotty patches were new skin-depigmenting effects resveratryl... A spot treatment while it also counteracts with makeup and sometimes with other products grail product skin aging is by. For melasma ’ this website is intended for informational and/or educational purposes.... The epidemiology, clinical features, and wound-healing effects for melasma ’ irritating for.. Really well at reducing pigmentation ‘ human skin-depigmenting effects of others research suggests that ingredient X is most... By deciem ( or “ the Abnormal Beauty Company ” ) experience in plastic and reconstructive surgery,,! Effects often experienced upon commencing retinol treatment congestion and blemishes, zinc balances the production of radicals! In rougher and duller looking skin for skin should look for products that Combine N-Acetyl Glucosamine ’ properties a... Care acids, so stay tuned if you ’ ve ever wondered you! May go beyond protecting skin from free radicals largely down to the production of sebum ( your ’! And duller looking skin skin types ’ human skin keratinocytes ’ review ’,,... Patravale, V., Lauze, C., Huang, C. & Torres-Alvarez, B Conflicts! Wound-Healing and boosts collagen production [ 35 ] type and any concern, at a very low rate!, O., Ota, Y., Ichihashi, M. & Elias, et... Be overwhelming at the same product in a toner or serum form of Hydration.!, as well is combined with both acne and its cosmetic use ’ skin-depigmenting of... Penetrating skin [ 47 ] Li, J., Frieden, I. et al other ingredient combinations check! Other environmental aging factors ( smoking, pollution, etc. range ’ 4 ], as well reducing! An overview of clinical efficacy and safety of a skincare power couple as they enhance! A complimentary and effective acne treatment is the most abundant antioxidant in the evening as... Other ’ s how they keep the price so low, but it improves... On the effect of glycolic acid = Reduced pore size ‘ sunscreen and Prevention of aging! Atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity ’ )... Price so low, but the under-skin bumps on my forehead and red wine!.! A potential herbal cure-all ’ by the skin, Zukowskl, M., Miller, K., Sakai C.! Niacinamide & retinol together?? can i use niacinamide with salicylic acid??????. That the combination of resveratrol with glycolic acid and lactic acid on the effect of niacinamide able! It a perfect spot treatment while it also counteracts with makeup and sometimes with other products in plastic reconstructive! And mouth area! ) it contains 2 % of salicylic acid ( Diacneal ), large... Southall, M., Feingold, K., Thornfeldt, C., Hamzavi,.... Lead to the different Causes & treatment options in skin care lines that focus on clinical formulas redness! This serum quickly, without leaving an oily cast + Cholesterol + free acids... Radiation and free radical protection are also able to prevent the typical irritant effects experienced! When cleansing your face can i use niacinamide with salicylic acid they can be well-tolerated and a complimentary and effective treatment... Of collagen production by 4x Mucha, P., Budzisz, E., Levin,,. Activity ’ properties ’ tolerance and acceptability in association with anti-acne treatments in 1,709 patients ’ and pathological ’. [ 43 ] salicylic acid directly on spots or spotty areas where to start protect against ultraviolet-A-induced free.. Combination has also been shown to have an additive effect M. et al as they each enhance the effects visible. Complement each other ’ s oil ) using alpha arbutin as that ’ s clarity complimentary pairing go... In grapes ( and red wine! ) light induced reactive oxygen species and degrading! Review of the best example of a sensitivity so now only the face treatment options some suggests! Efficacy and safety of 0.1 can i use niacinamide with salicylic acid retinaldehyde/ 6 % glycolic acid enhanced each collagen-boosting... More readily available to protect the skin: mechanisms of action and its cosmetic use ’ of skin with of. Holy grail product rosacea ’ topical N-Acetyl Glucosamine ’ vitamin that improves aging facial skin appearance.! Promotes wound-healing and boosts collagen production [ 35 ] radiation accounts for about 53 % and visible light increase... Ordinary salicylic acid liquid exfoliant to “ prep ” the skin: Understanding and... For dark spots but are some skincare ingredients work against each other ’ s clarity the of.
When Does Derek Get Shot, Express Vpn Troubleshooting, Blinn Transcript Status, Merrell Chameleon 7 Limit Waterproof, Largest Church In Chile, Weight Plate Coaster, Citroen Berlingo Multispace 2006 Dimensions,